Table 1.
Approximate annual cost of tenofovir-emtricitabine on the basis of how it is purchased.
| Approximate annual cost of tenofovir- emtricitabine |
Comments | Reference | |
|---|---|---|---|
| National average in 2006 | $9000 | Price factors in Medicaid reimbursement rates; expressed in 2006 dollars. Assuming 1.6% incident infection rate and 50% PrEP efficacy, this cost is associated with an ICER of $ 298000 per QALY gained. | [3] |
| Average wholesale price (AWP) in 2010 | $13416 | [2] | |
| Medicaid reimbursement rate in California, 2010 | $11 135a | Price calculated as AWP-17%. | [2] |
| Average out-of-pocket costs from four national drugstore chains in San Diego (2011) | $15 500 | Phone calls with pharmacy representatives | |
| San Diego Veterans Affairs Healthcare System (2011) | $6500a | Correspondence with a VA staff pharmacist | |
| Online search for generic formulation in Canada (2011) | $1300-3 650 | The quality of these websites cannot be verified and some websites do not require a prescription. | northdrugstore.com, northwestpharmacy.com |
| AIDS Drug Assistance Program of California (2011) | $11 470a | Data is not available to the public. Price cited is AWP-14.5%, but the final negotiated price likely includes further rebates. | Correspondence with ADAP representative |
ADAP, AIDS Drug Assistance Program; AWP, average wholesale price; PrEP, Pre-exposure prophylaxis; QALY, quality adjusted life year; VA, veterans affairs;
a
Medicaid, Veterans Affairs, and ADAP do not subsidize the cost of tenofovir-emtricitabine for off-label regimens such as PrEP. These values represent reimbursement rates for conventional use of the drug.