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. Author manuscript; available in PMC: 2015 Feb 1.
Published in final edited form as: Biol Psychiatry. 2013 Sep 13;75(3):10.1016/j.biopsych.2013.08.003. doi: 10.1016/j.biopsych.2013.08.003

Figure 2.

Figure 2

Pharmacological blockade of GSK3 reverses the deficit in LTP at MPP-DGC synapses. Summary plots of the magnitude of LTP induced by HFS at MPP-DGC synapses in slices from (A) WT mice with (n=6) and without (n=6) bath application of LiCl (20 mM), and (B) FX mice with (n=6) and without (n=9) bath application of LiCl (20 mM). (C) Data from WT mice (from A) and FX mice (bath application of LiCl from B) replotted to compare the magnitudes of LTP.(D) Summary of data A–C. (E) WT mice with (n=8) and without (n=12) bath application of CT99021 (2 uM). (F) FX mice with (n=7) and without (n=7) bath application of CT99021. (G) WT (from E) and FX (bath application of CT99021 from F) replotted to compare the magnitudes of LTP. *p<0.05 (Student’s t test). (H) Summary of data E–F