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. Author manuscript; available in PMC: 2013 Dec 28.
Published in final edited form as: Procedia Vaccinol. 2010;2(1):10.1016/j.provac.2010.03.013. doi: 10.1016/j.provac.2010.03.013

Fig. 1.

Fig. 1

Survival of BALB/c mice immunized with different recombinant proteins and challenged with B. mallei ATCC 23344 and B. pseudomallei 1026b.

BALB/c mice were challenged i.n. with 2 LD50 B. mallei 4 weeks following intranasal vaccination with BimA (n= 2), BopA (n=5), Combo (n=5), LolC (n=6), Hcp1 (n=8) or Control (n= 8). BopA- and BimA-vaccinated animals resulted in 100% survival up to 21 days post-challenge. (B) BALB/c mice (n = 15, pooled data from 3 separate experiments) were immunized 3 times with the indicated antigens, then challenged i.n. with 2 LD50 B. pseudomallei strain 1026b and survival times determined,.