Table 2.

Single nucleotide variations (SNVs) in 95 hallmark mutations within 12 oncogenes or tumor suppressor genes (AKT, BRAF, CDK4, Beta-catenin, EGFR, FBXW7, JAK2, c-KIT, KRAS, PDGFRA, PI3K, VEGF) probed in this experiment.

BRAF

BRAF_D594_1781A

BRAF_E586K_1756GA_Slp

BRAF_G464_1391G

BRAF_G466_1397G

BRAF_G466R_1396_GC

BRAF_G469_1407A

BRAF_K601E_AG

BRAF_K601N_A

BRAF_L597R_1790TG

BRAF_V600_1798G_1

BRAF_V600_1799T_1

BRAF_V600_1799T_2

BRAF_V600_1800G

KRAS

KRAS_A146_436

KRAS_G12_34G

KRAS_G12_35G

KRAS_G12_36T

KRAS_G13_37G

KRAS_G13_38G

KRAS_G13_39

KRAS_Q61_181C

KRAS_Q61_182A

KRAS_Q61_183A

Beta-catenin

CTNNB1_D32_94G

CTNNB1_D32_95A

CTNNB1_G34_101G

CTNNB1_S33_97T

CTNNB1_S37_109T

CTNNB1_S37_110C

CTNNB1_S45_133T

CTNNB1_S45_134C

CTNNB1_T41_121A

EGFR

EGFR_G719_G2155

EGFR_L858R_TG

EGFR_T790M_C2369T_Spl

VEGF

VEGF_5_1154_GA_ref

VEGF_5_1498_CT

VEGF_5_2573_CA

VEGF_5_634_GC_ref

cKIT

KIT_D816H_GC

KIT_D816V_AT

KIT_K642E_AG

KIT_L576P_TC

KIT_N556D_AG

KIT_R634W_CT

KIT_V559_T

KIT_V560D_TA_SPLICE

KIT_V825A_TC

KIT_Y553N_TA

PDGFR A

PDGFRA_D842_A2525T

PDGFRA_D842_G2524

PDGFRA_E996K_G2986

PDGFRA_N659K_C1977A

PDGFRA_N659Y_A1975T

PDGFRA_V561D_T1682A

PDGFRA_V824L_G2470C

FBXW7

FBWX7_R465C_C1393T

FBWX7_R465H_G1394A

FBWX7_R479_G1436

FBWX7_R505_G1514

FBWX7_R505C_C1513T

FBWX7_S582L_C1745T

FBXW7_H460R_A1379G

PI3K

PIK3CA_A1046V

PIK3CA_C420R

PIK3CA_E110K

PIK3CA_E418K

PIK3CA_E453K

PIK3CA_E542_1624G

PIK3CA_E545_1633G

PIK3CA_E545_1634A

PIK3CA_E545_1635G

PIK3CA_F909L

PIK3CA_G1049R

PIK3CA_H1047

PIK3CA_H1047_1

PIK3CA_H1047Y

PIK3CA_H701P

PIK3CA_K111N

PIK3CA_M1043V

PIK3CA_N345K

PIK3CA_P539R

PIK3CA_Q060K

PIK3CA_Q546_1636C

PIK3CA_Q546_1637A

PIK3CA_R088Q

PIK3CA_S405F

PIK3CA_T1025_3073A

PIK3CA_Y1021_3061T

PIK3CA_Y1021C_3062

AKT

AKT1_E17K_G49A

AKT2_E17K_G49A

AKT3_E17K_G49K

JAK2

JAK2_V617F_G1849T

cDK4

CDK4_R24C_C70T