Table 2.
Comparison between sonoclot parameters in different groups.
| Group | G1 | G2 | G3 | G4 | Control | |
|---|---|---|---|---|---|---|
| SONACT | Mean ± SD (s) | 176.31 ± 51.41 | 146.14 ± 41.76 | 130.09 ± 31.23 | 152.44 ± 13.22 | 137 ± 24.46 |
| Median (s) | 164 | 147 | 140 | 148 | 143.5 | |
| W C | 88* | 27* | 22* | 23* | — | |
|
| ||||||
| CR | Mean ± SD (u/min) | 29.41 ± 11.31 | 42.5 ± 17.64 | 44.54 ± 10.44 | 34.88 ± 11.54 | 31.6 ± 7.63 |
| Median (u/min) | 30 | 44.5 | 48 | 30 | 44 | |
| W C | 50* | 59* | 56* | 11* | — | |
|
| ||||||
| PF | Mean ± SD | 1.54 ± 1.08 | 2.29 ± 1.31 | 2.97 ± 0.84 | 1.36 ± 1.13 | 2.53 ± 0.76 |
| Median | 1.5 | 2.7 | 3.0 | 1.4 | 2.45 | |
| W C | 98* | 07¶ | 45* | 31* | — | |
|
| ||||||
| TP | Mean ± SD (min) | 20.5 ± 10.2 | 11.5 ± 7.6 | 9.5 ± 10.4 | 15.3 ± 11.9 | 11.8 ± 2.8 |
| Median | 17 | 9.5 | 6 | 10 | 11.5 | |
| W C | 116* | 18¶ | 44* | 11* | — | |
|
| ||||||
| PA | Mean ± SD (units) | 75.31 ± 25.13 | 91.07 ± 21.94 | 97.91 ± 8.61 | 71.94 ± 24.99 | 95.7 ± 7.48 |
| Median | 80 | 95 | 100 | 75 | 93.5 | |
| W C | 88* | 05¶ | 32* | 33* | — | |
|
| ||||||
| W T | 29 | 21 | 10 | 05 | — | |
G1: group 1 (decompensated cirrhosis), G2: group 2 (noncirrhotic liver disease), G3: group 3 (cirrhotic HCC), G4: group 4 (ACLF).
SONACT: sonoclot activated clotting time, CR: clot rate, PF: platelet function, TP: time to peak, PA: peak amplitude.
SD: standard deviation.
W C: calculated Wilcoxon test statistic (patient groups versus controls), W T: tabulated Wilcoxon critical value of alpha = 0.05 (W c > W T is considered to be statistically significant).
*Significantly different values as compared to control group.
¶Values are not significantly different as compared to controls.