Table 2.

Schedule of IR-dye conjugate nanoparticle treatments for biodistribution and elimination analysis.

No. ofmice	Oral formulations	Frequency	No. of administration	Time of analysis
n = 3	ZM4-IR (2.5 mg)	1/week	1	Elimination (metabolic cages): 12 hours after administration Time of collection of Odyssey images: 12–24–48–72 hours
n = 3	ZM4-IR (2.5 mg)	2/week	15	Time of collection of Odyssey images: before the new administration Sacrifice: 1 week, 1 month after last administration