Skip to main content
. Author manuscript; available in PMC: 2015 Jan 1.
Published in final edited form as: Biomaterials. 2013 Oct 4;35(1):10.1016/j.biomaterials.2013.09.032. doi: 10.1016/j.biomaterials.2013.09.032

Fig. 3.

Fig. 3

High-performance liquid chromatography-mass spectrometry (LC-MS) of latanoprost samples. Media containing latanoprost released over 1 day from a CL85:15, 45 demonstrated ion chromatograms (A) and annotated high-resolution mass spectra (B) that were substantially similar to those of unencapsulated commercial latanoprost. The mass spectra of both samples generated the same fragmentation pattern of the protonated ion [M + H]+ at m/z 433.29 for latanoprost, and produced abundant fragment ions at m/z 415.28 and 455.27, corresponding to a loss of water [M-H2O + H]+ and a sodium adduct [M + Na]+, respectively. m/z = mass to charge ratio.