Table 2.
Odds ratios, 95% confidence intervals, and P values for the optimal multivariable models
| Overall Cancer |
High-grade Cancer |
|||
|---|---|---|---|---|
| Variable | All Predictors Allowed | Volume, Number of Cores Not Allowed |
All Predictors Allowed | Volume, Number of Cores Not Allowed |
| PSA* | 2.70 | 2.56 | 3.39 | 3.24 |
| 2.45-2.97 | 2.35-2.78 | 2.94-3.90 | 2.85-3.67 | |
| P <.0001 | P <.0001 | P <.0001 | P <.0001 | |
| DRE | 2.53 | 2.89 | 2.75 | 3.06 |
| 1.93-3.33 | 2.27-3.69 | 1.87-4.04 | 2.20-4.27 | |
| P <.0001 | P <.0001 | P <.0001 | P <.0001 | |
| Age | 1.03 | 1.02 | 1.05 | 1.05 |
| 1.01-1.05 | 1.00-1.04 | 1.02-1.07 | 1.02-1.07 | |
| P = .001 | P = .02 | P = .001 | P = .0003 | |
| Race (African American) | – | – | – | – |
| Previous negative biopsy | 0.64 | |||
| – | 0.49-0.82 | – | – | |
| P = .0006 | ||||
| Family history | – | – | – | – |
| Volume* | 0.54 | 0.55 | ||
| 0.45-0.64 | Not allowed | 0.41-0.72 | Not allowed | |
| P <.0001 | P <.0001 | |||
| Number biopsy cores | – | Not allowed | – | Not allowed |
| AUASS | 0.98 | 0.97 | ||
| – | 0.97-1.00 | – | 0.95-1.00 | |
| P = .04 | P = .03 | |||
Abbreviations as in Table 1.
*
Corresponding to a change in odds for a doubling of the variable; – denotes not included in the model with lowest Bayesian Information Criterion.