Table 1.
Summary of strains
| Name | Alleles | O/E genea | MIC (mg/L) | Number/total |
|---|---|---|---|---|
| Strain Group 1 Clinical isolates, pre-1990, Fluconazole susceptible | ||||
| 978-14, 979-15, 979-33 | A/A | NA | <0.25 | 3/5 |
| 978-28 | A/G | NA | <0.25 | 1/5 |
| 979-05 | G/G | NA | <0.25 | 1/5 |
| Strain Group 2 Strains used in laboratories, Fluconazole susceptible | ||||
| SC5314, WO-1, SGY-243, 981, ATCC10261 | A/G | NA | <0.25 | 5/5 |
| Strain Group 3 Clinical isolates, Boston, MA, Fluconazole susceptible | ||||
| CI 072, CI 085, CI 159, CI 200, CI 210, CI 234, CI 237, CI 245, CI 247, CI 260, CI 285, CI 895, CI 898 | A/A | NA | <0.25 | 13/27 |
| CI 015, CI 050, CI 091, CI 105, CI 108, CI 116, CI 165, CI 183, CI 220, CI, 259, CI 267 | A/G | NA | <0.25 | 11/27 |
| CI 097, CI 138, CI 221 | G/G | NA | <0.25 | 3/27 |
| Strain Group 4 Clinical isolates, Boston, MA, Fluconazole resistant | ||||
| CI 158 | A/A | MDR1 | >128 | 11/22 |
| CI 122, CI 190 | A/A | CDR | >128 | |
| CI 113, CI 166, CI 167, CI 168, CI 177, CI 185, CI 199, CI 202 | A/A | unknown | >128 | 8/22 |
| CI 124 | A/G | CDR | >128 | |
| CI 125, CI 126, CI 128, CI 138, CI 172, CI 176, CI 189 | A/G | unknown | >128 | |
| CI 127, CI 187, CI 196 | G/G | unknown | >128 | 3/22 |
| Strain group 5 clinical isolates, Birmingham, AL, Fluconazole resistant | ||||
| AL 864, AL 868 | A/A | CDR | >128 | 10/11 |
| SH 855, AL 860, AL 861, AL 862, AL 863, AL 865, AL 866, AL 867 | A/A | unknown | >128 | |
| AL 859 | A/G | unknown | >128 | 1/11 |
NA not applicable
a
Overexpressed gene