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. 2013 Dec 30;7:44. doi: 10.3389/fnana.2013.00044

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Copyright © 2013 Fang, He, Zhang, Hu, Yang, Jiang and Han.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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TNF-α expression decreased markedly in both the spinal cord (A,C) and cerebral cortex (B,D) following treatment with CNTF or C16, as compared with the vehicle control, at weeks 2 and 8 post-immunization, as shown by Western blotting. (E,F) TNF-α expression in the spinal cord and brain cortex at week 2 (E) and week 8 (F) postimmunization revealed by Western blotting. ^aP < 0.05 versus normal control; ^bP < 0.05 versus vehicle-treated EAE rats; ^cP < 0.05 versus C16-treated EAE rats; ^dP < 0.05 versus CNTF-treated EAE rats.