. Author manuscript; available in PMC: 2014 Oct 1.

Published in final edited form as: Acad Radiol. 2013 Oct;20(10):10.1016/j.acra.2013.07.010. doi: 10.1016/j.acra.2013.07.010

Table 2. Theoretical and Measured Effective MW, T1 Relaxivities, and Blood Half-Lives for PEG12,000-Gen4-(Gd-DOTA) and Albumin-(Gd-DTPA)₃₅.

Contrast Agent	Theoretical MW (kDa)	Effective MW (kDa)	T1 Relaxivity per Gd Ion (mM⁻¹·s⁻¹)	Blood Half-Life Mean ± SD (Minutes)
PEG12,000-Gen4-(Gd-DOTA)₁₆	27	194	9.9	49 ± 6
Albumin-(Gd-DTPA)₃₅	92	180	10.4	54 ± 11

MW, molecular weight; PEG, polyethylene glycol; SD, standard deviation.

Effective molecular weights were determined by comparison to protein standards on size exclusion chromatography. T1 relaxivities were measured at 10 MHz and 37°C.

Table 2. Theoretical and Measured Effective MW, T1 Relaxivities, and Blood Half-Lives for PEG12,000-Gen4-(Gd-DOTA) and Albumin-(Gd-DTPA)35.

Table 2. Theoretical and Measured Effective MW, T1 Relaxivities, and Blood Half-Lives for PEG12,000-Gen4-(Gd-DOTA) and Albumin-(Gd-DTPA)₃₅.