Table 2. Cross-sectional associations of APOE alleles with prevalent CKD.
| APOE allele OR (95% CI) |
|||
|---|---|---|---|
| ε3 | ε2 | ε4 | |
| eGFRcreat | |||
| N | 2,470 | 513 | 861 |
| #CKD | 634 | 132 | 184 |
| Unadjusted | 1.00 (reference) | 0.99 (0.81, 1.20) | 0.79 (0.67, 0.93) |
| Age + gender adjusted | 1.00 (reference) | 0.97 (0.79, 1.18) | 0.82 (0.69, 0.98) |
| Fully adjusted* | 1.00 (reference) | 1.01 (0.82, 1.25) | 0.80 (0.68, 0.96) |
| eGFRcys | |||
| N | 2,470 | 513 | 861 |
| #CKD | 693 | 143 | 200 |
| Unadjusted | 1.00 (reference) | 0.97 (0.81, 1.17) | 0.77 (0.66, 0.91) |
| Age + gender adjusted | 1.00 (reference) | 0.92 (0.75, 1.12) | 0.81 (0.68, 0.96) |
| Fully adjusted* | 1.00 (reference) | 0.88 (0.71, 1.09) | 0.83 (0.69, 0.99) |
*Fully adjusted model includes age, gender, diabetes, systolic blood pressure, diastolic blood pressure, antihypertensive medications, body mass index and prevalent coronary heart disease, low density lipoprotein, high density lipoproteins, triglycerides, lipid lowering medication use, and smoking status.