Table 1.
Measurements of weight, plasma glucose, serum creatinine, water intake and urine output and mitochondrial respiration between control, STZ and STZ + insulin groups. Data are represented as means ± SEM of % of control (N ≥ 3 for each group).
Control | STZ | STZ + Insulin | |
---|---|---|---|
Body Weight (g) | 440 ± 19 | 285 ± 22*# | 395 ± 20 |
Plasma Glucose (mg/dL) | 128 ± 17 | 408 ± 25*# | 189 ± 33 |
Serum Creatinine (mg/dL) | 0.9 ± 0.3 | 1.0 ± 0.5 | 1.1 ± 0.4 |
Water Intake (mL) | 40 ± 3 | 125 ± 10*# | 44 ± 5 |
Urine Output (mL/24 hr) | 10 ± 1 | 42 ± 5*# | 15 ± 3 |
State 2 Respiration (nmol O2/mg protein/min) | 52 ± 8 | 92 ± 10*# | 49 ± 12 |
State 3 Respiration (nmol O2/mg protein/min) | 162 ± 12 | 145 ± 15 | 172 ± 11 |
Labels with * are statistically different from control and # are statistically different from STZ + Insulin (p ≤ 0.05).