Table 3.
Differentially expressed genes in hypothalamus of WRR and XH chickens
| Gene symbol | Gene title | P value | Fold-change | Chromosomes alignment |
|---|---|---|---|---|
|
Lipid metabolic process | ||||
|
P20K |
quiescence-specific protein |
0,0109 |
-2,402 |
chr17:881078-883996 |
|
Porphyrin biosynthetic process | ||||
|
FECH |
ferrochelatase (protoporphyria) |
0,009 |
-2,155 |
chrZ:267090-278253 |
|
Nitrogen compound metabolic process | ||||
|
RCJMB04_35g11 |
vanin 1 |
0,0406 |
-2,312 |
chr3:58745711-58758866 |
|
Transport | ||||
|
PMP2 |
peripheral myelin protein 2 |
0,031 |
3,405 |
chr2:126148069-126152515 |
|
Ion transport | ||||
|
SLC22A2 |
solute carrier family 22 (organic cation transporter), member 2 |
0,004 |
-2,123 |
chr3:47342914-47355320 |
|
GLRA1 |
glycine receptor, alpha 1 (startle disease/hyperekplexia) |
0,035 |
-2,146 |
chr13:12903161-12940509 |
|
sodium ion transport | ||||
|
SLC13A5 |
solute carrier family 13 (sodium-dependent citrate transporter), member 5 |
0,003 |
-2,046 |
chr19:9754843-9769124 |
|
Copper ion transport | ||||
|
SLC31A1 |
solute carrier family 31 (copper transporters), member 1 |
0,017 |
7,335 |
chr17:1874758-1884555 |
|
Striated muscle contraction | ||||
|
MYBPC2 |
myosin binding protein C, fast type |
0,034 |
-3,717 |
un |
|
Response to stress | ||||
|
HSP70 |
heat shock protein 70 |
0,001 |
-2,093 |
chr5:55409752-55412248 |
|
HSP25 |
heat shock protein 25 |
0,006 |
-2,759 |
chr27:4486260-4487251 |
|
Signal transduction | ||||
|
LOC419724 |
similar to KIAA0712 protein |
0,009 |
-2,393 |
chr24:1172171-1264246 |
|
cyclic nucleotide catabolic process | ||||
|
N4BP2L1 |
NEDD4 binding protein 2-like 1 |
0,006 |
3,732 |
chr1:178835487-178837064 |
|
Negative regulation of endothelial cell proliferation | ||||
|
TNFSF15 |
tumor necrosis factor (ligand) superfamily, member 15 |
0,027 |
2,553 |
chr17:2943951-2959613 |
|
Regulation of transcription, DNA-dependent | ||||
|
CREB3L2 |
cAMP responsive element binding protein 3-like 2 |
0,001 |
-2,197 |
chr1:59488049-59500378 |
|
MLL3 |
myeloid/lymphoid or mixed-lineage leukemia 3 |
0,008 |
-4,110 |
chr2:6484781-6486027 |
|
Protein complex assembly | ||||
|
ATPAF1 |
ATP synthase mitochondrial F1 complex assembly factor 1 |
0,003 |
-3,241 |
chr8:22570693-22574048 |
|
Protein amino acid phosphorylation | ||||
|
PRKD3 |
protein kinase D3 |
0,0005 |
-2,745 |
chr3:34793675-34819927 |
|
SGK1 |
serum/glucocorticoid regulated kinase 1 |
0,004 |
2,419 |
chr3:58130872-58134430 |
|
RIPK2 |
receptor-interacting serine-threonine kinase 2 |
0,013 |
2,532 |
chr2:129010265-129029220 |
|
Proteolysis | ||||
|
FOLH1 |
folate hydrolase (prostate-specific membrane antigen) 1 |
0,005 |
-2,344 |
chr1:191872775-191933212 |
|
C1R |
complement component 1, r subcomponent |
0,011 |
-2,014 |
chr1:80553474-80558910 |
|
ITGBL1 |
integrin, beta-like 1 (with EGF-like repeat domains) |
0,024 |
2,43 |
chr1:147579457-147711379 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0,041 | -2,155 | chr2:133389475-133390863 |
Positive values simply mean that the genes were up-regulated when WRR chickens are compared with XH chickens.
Similarly, negative values mean down-regulation when comparison between WRR and XH chickens is made, Data were significantly different [P > 0, 05 (fold change ≥ 2)].