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. 2013 Dec 10;171(1):107–121. doi: 10.1111/bph.12434

Figure 16.

Figure 16

Graphical representation showing the effect of methionine on osteoclast development. Methionine inhibits the propensity of blood mononuclear cells to develop into functional osteoclasts in osteoporotic animals by down-regulation of the TLR4/MyD88/NF-κB signalling pathway.