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. 2013 Dec 10;171(1):253–264. doi: 10.1111/bph.12441

Table 2.

The ED50 of the antinociceptive effects of i.t. oxycodone and morphine

ED50 (nmol) Vehicle Tertiapin-Q Shift ratio (T/V)
Oxycodone 3.51 (2.04–6.05) 15.58 (9.03–26.9) 4.44
Morphine 0.28 (0.17–0.48) 1.48 (0.73–3.01) 5.29

The ED50 values were determined by linear regression using data from at least four doses for each opioid. Values in parentheses indicate the 95% confidence range. The shift ratio (T/V) shows relative potency of the ED50 values between vehicle group (V) and tertiapin-Q group (T). The ratio (O/M) represents relative efficacy of oxycodone over that of morphine.