Table 1.
Date for the 10 cases
| Case | Age/sex | Nocturnal pain/BW loss | Delayed diagnosis (month) | Radiography | MRI | Preoperative diagnosis | Underlying disease | Treatment (antibiotics/weeks) | WBC/mm 3 | ESR (mm/h)/ CRP (mg/L) | Recurrence/pathological fracture/surgery times | culture |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |
57/M |
+/- |
4 |
Moth-eaten osteolysis |
|
Ewing sarcoma |
|
S+D+C (36) |
10500 |
132/12.7 |
+/+/4 |
Klebsiella pneumoniae |
| |
|
|
|
Laminated periosteal reaction |
|
|
|
|
|
|
|
|
| 2 |
33/M |
+/+ |
6 |
Moth-eaten osteolysis |
|
Ewing sarcoma |
Drug abuser |
S+D+C+O (40) |
19900 |
Nil/15.4 |
+/+/4 |
Klebsiella pneumoniae |
| |
|
|
|
Laminated periosteal reaction |
|
|
|
|
|
|
|
|
| 3 |
54/F |
+/- |
3 |
Moth-eaten osteolysis |
Cortex destruction Soft tissue mass |
Ewing sarcoma |
DM |
S+D+C+O (9) |
10400 |
Nil/7.29 |
-/-/1 |
Klebsiella pneumoniae |
| |
|
|
|
Laminated periosteal reaction |
|
|
|
|
|
|
|
|
| 4 |
37/F |
-/- |
1 |
Moth-eaten osteolysis |
Cortex destruction |
Leukemia |
DM |
S+D+C+O (4) |
16500 |
91/12.9 |
-/-/1 |
Klebsiella pneumoniae |
| |
|
|
|
Monolayer periosteal reaction |
Penumbra sign |
|
|
|
|
|
|
|
| 5 |
37/M |
-/- |
8 |
Moth-eaten osteolysis Laminated periosteal reaction |
|
Ewing sarcoma |
DM |
S+D+C+O (44) |
16600 |
Nil/21.6 |
+/+/2 |
Klebsiella pneumoniae |
| 6 |
14/M |
+/ + |
4 |
Osteolysis Laminated periosteal reaction |
Extensive soft tissue |
Ewing sarcoma |
|
Casting (15) |
7000 |
45/0.95 |
+/+/1 |
Staphylococcus aureus |
| 7 |
13/M |
-/- |
1 |
Hyperostosis Septated periosteal reaction |
Extensive soft tissue |
Malignant change of osteomyelitis |
DM |
S+D+C (4) |
12200 |
68/13 |
-/-/1 |
Klebsiella pneumoniae |
| 8 |
30/M |
+/- |
4 |
Osteolysis |
Soft tissue mass Cortex destruction |
Metastatic lesion |
|
S+D+C (6) |
11000 |
58/1.13 |
-/-/ 1 |
Staphylococcus aureus |
| |
|
|
|
Laminated periosteal reaction |
|
|
|
|
|
|
|
|
| 9 |
50/F |
+/+ |
5 |
Osteolysis |
Periosteal reaction |
|
|
S+D+C (42) |
10800 |
93/13.7 |
+/-/2 |
Staphylococcus aureus |
| |
|
|
|
Laminated periosteal reaction |
|
|
|
|
|
|
|
|
| 10 |
54/F |
+/- |
3 |
Hyperostosis |
Enhancing lesion |
Metastatic tumors |
|
S+D+C (4) |
8700 |
NIL/1.15 |
-/-/1 |
Propionibacterium |
| |
|
|
|
Laminated periosteal reaction |
|
|
|
|
|
|
|
|
| Summary |
|
Night pain: 7 |
AVG: 3.9 |
|
|
|
DM: 4 |
AVG: 20.4 weeks |
Elevated: 8 |
Elevated CRP (>0.5 mg/L): 10 |
Recurrence/fracture: 5/4 |
|
| Weight loss: 3 | Drug abuser: 1 |
BW, body weight; CRP, C-reactive protein; DM, diabetes mellitus; ESR, erythrocyte sedimentation rate; MRI, magnetic resonance imaging; S+D+C+O, sequestrectomy + debridement + bone cement + open reduction internal fixation; WBC, white blood cell.