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. 2013 Oct 22;11:283. doi: 10.1186/1477-7819-11-283

Table 1.

Date for the 10 cases

Case Age/sex Nocturnal pain/BW loss Delayed diagnosis (month) Radiography MRI Preoperative diagnosis Underlying disease Treatment (antibiotics/weeks) WBC/mm 3 ESR (mm/h)/ CRP (mg/L) Recurrence/pathological fracture/surgery times culture
1
57/M
+/-
4
Moth-eaten osteolysis
 
Ewing sarcoma
 
S+D+C (36)
10500
132/12.7
+/+/4
Klebsiella pneumoniae
 
 
 
 
Laminated periosteal reaction
 
 
 
 
 
 
 
 
2
33/M
+/+
6
Moth-eaten osteolysis
 
Ewing sarcoma
Drug abuser
S+D+C+O (40)
19900
Nil/15.4
+/+/4
Klebsiella pneumoniae
 
 
 
 
Laminated periosteal reaction
 
 
 
 
 
 
 
 
3
54/F
+/-
3
Moth-eaten osteolysis
Cortex destruction Soft tissue mass
Ewing sarcoma
DM
S+D+C+O (9)
10400
Nil/7.29
-/-/1
Klebsiella pneumoniae
 
 
 
 
Laminated periosteal reaction
 
 
 
 
 
 
 
 
4
37/F
-/-
1
Moth-eaten osteolysis
Cortex destruction
Leukemia
DM
S+D+C+O (4)
16500
91/12.9
-/-/1
Klebsiella pneumoniae
 
 
 
 
Monolayer periosteal reaction
Penumbra sign
 
 
 
 
 
 
 
5
37/M
-/-
8
Moth-eaten osteolysis Laminated periosteal reaction
 
Ewing sarcoma
DM
S+D+C+O (44)
16600
Nil/21.6
+/+/2
Klebsiella pneumoniae
6
14/M
+/ +
4
Osteolysis Laminated periosteal reaction
Extensive soft tissue
Ewing sarcoma
 
Casting (15)
7000
45/0.95
+/+/1
Staphylococcus aureus
7
13/M
-/-
1
Hyperostosis Septated periosteal reaction
Extensive soft tissue
Malignant change of osteomyelitis
DM
S+D+C (4)
12200
68/13
-/-/1
Klebsiella pneumoniae
8
30/M
+/-
4
Osteolysis
Soft tissue mass Cortex destruction
Metastatic lesion
 
S+D+C (6)
11000
58/1.13
-/-/ 1
Staphylococcus aureus
 
 
 
 
Laminated periosteal reaction
 
 
 
 
 
 
 
 
9
50/F
+/+
5
Osteolysis
Periosteal reaction
 
 
S+D+C (42)
10800
93/13.7
+/-/2
Staphylococcus aureus
 
 
 
 
Laminated periosteal reaction
 
 
 
 
 
 
 
 
10
54/F
+/-
3
Hyperostosis
Enhancing lesion
Metastatic tumors
 
S+D+C (4)
8700
NIL/1.15
-/-/1
Propionibacterium
 
 
 
 
Laminated periosteal reaction
 
 
 
 
 
 
 
 
Summary
 
Night pain: 7
AVG: 3.9
 
 
 
DM: 4
AVG: 20.4 weeks
Elevated: 8
Elevated CRP (>0.5 mg/L): 10
Recurrence/fracture: 5/4
 
    Weight loss: 3         Drug abuser: 1          

BW, body weight; CRP, C-reactive protein; DM, diabetes mellitus; ESR, erythrocyte sedimentation rate; MRI, magnetic resonance imaging; S+D+C+O, sequestrectomy + debridement + bone cement + open reduction internal fixation; WBC, white blood cell.