Table 1. Volume of Vitamin B12 Laboratory Tests in Ontario for Fiscal Years 2005/2006 to 2010/2011

Table 2. Summary of Laboratory Tests to Assess Vitamin B12 Deficiency

Table 3. Guidelines for Assessment of Vitamin B12 Levels

Table 4. Body of Evidence Examined According to Study Design

Table 5. Summary of Systematic Reviews Examining the Association Between Vitamin B12 (or Hyperhomocysteinemia) and the Onset of Dementia

Table 6. Studies Included in Highest-Scoring Systematic Reviews, Sorted by Length of Observation Period

Table 7. Studies Included in Systematic Reviews of the Effectiveness of Vitamin B12 on Cognitive Function

Table 8. Randomized Controlled Trials Comparing Oral Vitamin B12 to Intramuscular Vitamin B12 in Patients with Vitamin B12 Deficiency

Table A1. Systematic Reviews of Treatment with B12 for Cognitive Function

Table A2. GRADE Evidence Profile for the Association Between Homocysteine and the Onset of Dementia

Table A3. Risk of Bias Among Observational Trials for the Association Between Homocysteine and the Onset of Dementia

Table A4. GRADE Evidence Profile for Comparison of B Vitamins Versus Placebo

Table A5. Risk of Bias Among Randomized Controlled Trials for Comparison of B Vitamins Versus Placebo

Table A6. GRADE Evidence Profile for Comparison of Oral Vitamin B12 and Parenteral Vitamin B12

Table A7. Risk of Bias Among Randomized Controlled Trials for Comparison of Oral Vitamin B12 and Parenteral Vitamin B12