Table 1.
IC 50 effect of tested compounds on oxidative burst of whole blood, isolated PMNs, T-cell proliferation and IL-2 cytokine
Comp. Code |
Oxidative burst IC
50
(μM) on |
T- Cell proliferation IC 50 (μM) | IC 50 IL-2 (μM) | |
---|---|---|---|---|
Whole blood | PMNs | |||
1 |
>333.33 |
>166.67 |
>166.67 |
>166.67 |
2 |
>331.13 |
>165.56 |
<10.33 |
16.89 ± 1.32 |
3 |
>328.95 |
>164.47 |
42.11 ± 11.51 |
49.34 ± 1.32 |
Control Aa |
11.2 ± 1.9 |
2.8 ± 0.8 |
- |
- |
Control Bb | - | - | 0.2 | <0.5 |
aIbuprofen; bPrednisolone.