Skip to main content
. Author manuscript; available in PMC: 2013 Dec 30.
Published in final edited form as: Curr Opin Microbiol. 2008 Oct 3;11(5):10.1016/j.mib.2008.08.003. doi: 10.1016/j.mib.2008.08.003

Figure 2.

Figure 2

The nascent peptide exit tunnel. 3’ ends of aminoacyl- and peptidyl-tRNAs converge in the peptidyl transferase center where assembly of amino acids into a polypeptide takes place. The nascent peptide traverses the body of the large ribosomal subunit through the exit tunnel whose outside surface is shown in yellow and inside surface is shown in blue. The tunnel walls are formed primarily by segments of rRNA but extended loops of ribosomal proteins L4 and L22 reach the tunnel near its constriction close to where the macrolide binding site is located. The location of the peptidyl transferase center and of the macrolide binding site near the tunnel constriction are indicated. Reproduced with minor changes from [36].