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. Author manuscript; available in PMC: 2014 Sep 1.
Published in final edited form as: Cornea. 2013 Sep;32(9):10.1097/ICO.0b013e318296e0b9. doi: 10.1097/ICO.0b013e318296e0b9

Figure 2.

Figure 2

Antagonizing PDGF-receptor alters PDGF-induced loss of TKT. RCK cultured for 4 days in serum-free medium without [PDGF(-)] or with 100 ng/ml PDGF-BB [PDGF(+)] in conjunction without [(-), solid bars] or with [(+), striped bar] 10 μM ST1571 (Gleevec). Representative immunoblot of cytoplasmic lysates probed for TKT and beta-actin (top panel). Graph of immunoblot data (bottom panel). Relative TKT protein, a ratio of the TKT to the beta-actin band densities for each immunoblot (n=2), expressed as average ± high/low. TKT bands are ∼70 kD and beta-actin bands are ∼42 kD based on molecular size markers (not shown).