Table 3.
a. Univariate and multivariate logistic results, Diagnostic and Screening populations, Houston, TX and Vancouver, BC, 1999-2005.
| Univariate POR (95% CI) | p Value | Multivariate POR (95% CI) | p Value | |
|---|---|---|---|---|
|
| ||||
| Race | ||||
|
| ||||
| White | 1.00 | -- | 1.00 | -- |
|
| ||||
| Black | 0.55 (0.42-0.73) | <0.001 | 0.29 (0.19-0.43) | <0.0001 |
|
| ||||
| Hispanic | 0.37 (0.29-0.47) | <0.001 | 0.24 (0.17-0.35) | <0.0001 |
|
| ||||
| Other | 1.16 (0.84-1.59) | <0.372 | 1.14 (0.71-1.83) | <0.597 |
|
| ||||
| Age* | ||||
|
| ||||
| Years | 0.95 (0.94-0.96) | <0.001 | 0.99 (0.97-1.01) | <0.210 |
|
| ||||
|
Annual Household Income
|
||||
| Low ($0-$19,999) | 1.00 | -- | ||
| Medium ($20,000-$49,999) | 0.80 (0.61-1.04) | <0.094 | ||
| High (> $50,000) | 0.81 (0.62-1.06) | <0.127 | ||
| Don’t Know/Refused | 1.61 (1.12-2.34) | <0.010 | ||
|
| ||||
| Education Level | ||||
|
| ||||
| < High School | 1.00 | -- | 1.00 | -- |
|
| ||||
| HS Graduate/Some College | 0.66 (0.47-0.93) | <0.016 | 0.46 (0.28-0.77) | <0.003 |
|
| ||||
| College Graduate | 0.70 (0.49-1.01) | <0.056 | 0.43 (0.25-0.76) | <0.003 |
|
| ||||
| Advanced Degree | 0.53 (0.35-0.82) | <0.004 | 0.49 (0.26-0.92) | <0.026 |
|
| ||||
|
Employment Status
|
||||
| Full Time | 1.00 | -- | ||
| Part Time | 1.01 (0.76-1.33) | <0.969 | ||
| Retired/Housewife/Student | 0.99 (0.79-1.24) | <0.938 | ||
| Unemployed | 1.09 (0.77-1.55) | <0.635 | ||
|
| ||||
|
Martial Status
| ||||
| Not Married | 1.00 | -- | ||
| Married | 0.86 (0.75-0.98) | <0.028 | ||
|
| ||||
|
Smoking
| ||||
| Ever, No | 1.00 | -- | ||
| Ever, Yes | 1.56 (1.29-1.88) | <0.001 | ||
|
| ||||
|
Alcohol Use
| ||||
| No | 1.00 | -- | ||
| Yes | 1.44 (1.18-1.75) | <0.001 | ||
|
| ||||
|
b. Univariate and multivariate logistic results, Diagnostic and Screening populations, Houston, TX and Vancouver, BC, 1999-2005.
| ||||
| Genital Infections | ||||
|
| ||||
| Any, No | 1.00 | -- | 1.00 | -- |
|
| ||||
| Any, Yes | 1.93 (1.56-2.38) | <0.001 | 2.17 (1.61-2.92) | <0.0001 |
|
| ||||
| Menopausal Status | ||||
|
| ||||
| Premenopausal | 1.00 | -- | 1.00 | -- |
|
| ||||
| Perimenopausal | 0.15 (0.09-0.23) | <0.001 | 0.22 (0.12-0.41) | <0.0001 |
|
| ||||
| Postmenopausal | 0.32 (0.25-0.40) | <0.001 | 0.68 (0.42-1.09) | <0.106 |
|
| ||||
|
Parity
|
||||
| ≤ 2 | 1.00 | -- | ||
| 3+ | 0.73 (0.61-0.89) | <0.001 | ||
|
|
|
|||
| Current Oral Contraceptive Use | ||||
|
| ||||
| No | 1.00 | -- | 1.00 | -- |
|
| ||||
| Yes | 4.37 (3.28-5.82) | <0.001 | 2.31 (1.53-3.47) | <0.0001 |
|
| ||||
|
Current Condom Use
|
||||
| No | 1.00 | -- | ||
| Yes | 1.53 (1.20-1.95) | <0.001 | ||
|
|
|
|||
| HPV Status (as detected by HCII) | ||||
|
| ||||
| Negative | 1.00 | -- | 1.00 | -- |
|
| ||||
| Low-risk Type(s) | 2.99 (1.59-5.62) | <0.001 | 3.43(1.33-8.84) | <0.011 |
|
| ||||
| High-risk Type(s) | 8.60 (6.58-11.23) | <0.001 | 2.08 (1.44-3.03) | <0.0001 |
|
| ||||
| Consensus | 9.77 (5.30-18.00) | <0.001 | 3.46 (1.39-8.60) | <0.008 |
|
| ||||
|
HPV 16 DNA
|
||||
| Absent | 1.00 | -- | ||
| Present | 1.92 (1.51-2.44) | <0.001 | ||
|
| ||||
|
HPV 18 DNA
| ||||
| Absent | 1.00 | -- | ||
| Present | 1.11 (0.84-1.46) | <0.473 | ||
|
| ||||
| Consensus HPV DNA | ||||
|
| ||||
| Absent | 1.00 | -- | 1.00 | -- |
|
| ||||
| Present | 2.69 (2.08-3.46) | <0.001 | 1.66 (1.21-2.28) | <0.002 |
|
| ||||
| Worst Histology | ||||
|
| ||||
| Negative | 1.00 | -- | 1.00 | -- |
|
| ||||
| Atypia/HPV Assoc. Changes | 2.28 (1.82-2.86) | <0.001 | 1.86 (1.41-2.44) | <0.0001 |
|
| ||||
| LSIL | 15.38 (9.22-25.67) | <0.001 | 6.39 (3.48-11.75) | <0.0001 |
|
| ||||
| HSIL/CIS/SCC | 39.88 (23.49-67.68) | <0.001 | 12.08 (6.25-23.32) | <0.0001 |
*
Although age was statistically insignificant, its exclusion results in marked influence on the other variables, and thus was included.