Table 2.
Minimal inhibitory concentrations of the extracts and fractions from Hymenaea stigonocarpa against Gram-positive cocci.
Gram-positive cocci | Origin | Minimal inhibitory concentrations (μg/mL) | Resistance phenotype | ||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
CE | EAE | EE | AE | HE | AF | EAF | OXA | TEI | |||
Staphylococcus aureus ATCC 25293 | ATCC | 512 | 512 | 256 | 512 | 128 | 128 | 128 | 0.12 | — | Control strain |
Staphylococcus aureus ATCC 33591 | ATCC | 1024 | 512 | 256 | 512 | 256 | 256 | 512 | 64 | — | Control strain |
Staphylococcus aureus LFBM 05 | Hemoculture | 1024 | 512 | 256 | 512 | 256 | 125 | 512 | 32 | — | AMP, AZI, CFO, PEN |
Staphylococcus aureus LFBM 11 | ND | 512 | 512 | 128 | 128 | 128 | 128 | 256 | 1.0 | — | PEN |
Staphylococcus aureus LFBM 13 | Vaginal secretion | 512 | 512 | 512 | 512 | 128 | 64 | 512 | 1.0 | — | PEN |
Staphylococcus aureus LFBM 15 | Sputum | 512 | 512 | 128 | 512 | 64 | 64 | 256 | 0.12 | — | PEN, GET, ERI, CLI |
Staphylococcus aureus LFBM 16 | Hemoculture | 512 | 512 | 256 | 512 | 256 | 125 | 256 | 0.12 | — | AMP, AZI, CFO, PEN |
Staphylococcus aureus LFBM 25 | Hemoculture | 512 | 512 | 256 | 512 | 256 | 256 | 256 | 256 | — | PEN, GET, ERI, RIF, CLI |
Staphylococcus aureus LFBM 26 | Hemoculture | 512 | 512 | 256 | 512 | 64 | 64 | 512 | 256 | — | AMC, AMP, CFO, CIP |
Staphylococcus aureus LFBM 28 | Tracheal secretion | 1024 | 512 | 256 | 512 | 256 | 128 | 512 | 16 | — | AMC, CIP, CFO, GET |
Staphylococcus aureus LFBM 29 | Hemoculture | 1024 | 512 | 256 | 512 | 256 | 256 | 512 | 8.0 | — | AMC, AMP, CFO, PEN |
Staphylococcus aureus LFBM 30 | Tracheal secretion | 1024 | 512 | 256 | 512 | 256 | 256 | 512 | 16 | — | AMC, AMP, CFO, CIP |
Enterococcus faecalis LFBM 02 | Hemoculture | 1024 | 512 | 256 | 256 | 256 | 256 | 512 | — | 8.0 | CIP, PEN, ERI, IMI, TET |
Enterococcus faecalis LFBM 07 | Hemoculture | 1024 | 512 | 256 | 512 | 512 | 256 | 512 | — | 8.0 | CIP, PEN, ERI, IMI, TET |
Enterococcus faecalis LFBM 08 | Urine | 1024 | 512 | 256 | 512 | 256 | 256 | 512 | — | 0.25 | None antibiotic |
Enterococcus faecalis LFBM 18 | Hemoculture | 1024 | 512 | 256 | 512 | 256 | 256 | 512 | — | 4.0 | CIP, PEN, ERI, IMI, TET |
ATCC: American Type Culture Collection; CE: cyclohexanic extract; EAE: ethyl acetate extract; EE: ethanolic extract; AE: aqueous extract; HE: hydroalcoholic extract; AF: aqueous fraction; EAF: ethyl acetate fraction; OXA: oxacillin; AMP: ampicillin; AZI: azithromycin; CFO: cefoxitin; CIP: ciprofloxacin; GET: gentamicin; PEN: penicillin; CLI: clindamycin; ERI: erythromycin; IMI: imipenem; RIF: rifampin; TET: tetracycline; LFBM: Laboratório de Fisiologia e Bioquímica de Microorganismos; ND: not determined.