Table 1.

Composition per vial of prothrombin complex concentrate 500 units¹

Ingredient	Quantity
Total protein	120 to 280 mg
Factor II	380 to 800 units
Factor VII	200 to 500 units
Factor IX	400 to 620 units
Factor X	500 to 1,020 units
Protein C	420 to 820 units
Protein S	240 to 680 units
Heparin	8 to 40 units
Antithrombin III	4 to 30 units
Human albumin	40 to 80 mg
Sodium chloride	60 to 120 mg
Sodium citrate	40 to 80 mg
Hydrochloric acid	Small amounts
Sodium hydroxide	Small amounts