. 2013 Dec 9;48(11):951–957. doi: 10.1310/hpj4811-951

Table 2.

Median INR after start of infusion of prothrombin complex concentrate or plasma in patients treated with warfarin¹

	Prothrombin complex concentrate (n = 98)	Plasma (n = 104)
Baseline	3.9	3.6

30 minutes	1.2^a	2.4

1 hour	1.3^a	2.1

2 to 3 hours	1.3^a	1.7

6 to 8 hours	1.3^a	1.5

12 hours	1.2^a	1.4

24 hours	1.2	1.3

Note: INR = international normalized ratio.

Statistically significant difference compared with plasma by 2-sided Wilcoxon test.