Table 1.

Pore geometries and measured and calculated conductances in 1MKCl. The calculated conductance is based on electrolyte resistivity (G Calc. 1), and on solution of Poisson-Nernst-Planck-Stokes equations (G Calc. 2). These are in good agreement with measurements. There is a significant increase in conductance when even small amounts of DNA are added to the input reservoir.

Pore Depth	Pore Diameter (nm)	G 1M KCl (nS)	G Calc. 1 (nS)	G Calc. 2 (nS)	G KCl+DNA (nS)
30 nm SiN + 10 nm Pd	3.0	2.9	2.57	2.56	4.0
10 nm SiN + 10 nm Pd	4.2	9.7	9.58	9.53	48.5