FIG. 4.
Trophosphere detachment mechanics. Trophospheres are detached from sialyl Lewis X (sLeX)-coated slides (n=16) under 2.74×10−3 dyn of force and 7.5×10−5 dyn-cm of torque. Blocking with MECA-79 (n=17) decreases necessary detachment force and torque by 56% and 68%, respectively. Bare polycarbonate (n=10) plastic and 10% bovine serum albumin (n=12)-coated slides are used as controls. Statistical analysis performed using one-way ANOVA, with Tukey post hoc tests of significance signified by stars, *p<0.05 and **p<0.01.