Table 2.
Effect of C. pentandra on OGTT of normal healthy and STZ induced diabetic rats
| Groups | Treatment & Dose (p.o.) |
Fasting Blood sugar level (mg/dL) at various time intervals | ||||
| 0 min | 30 min | 60 min | 90 min | 120 min | ||
| I | Vehicle control | 82.00 ± 1.21 | 181.20 ± 0.60 | 175.50 ± 1.40 | 155.70 ± 1.40 | 129.3 ± 0.49 |
| II |
C. pentandra extract (200 mg/kg) |
84.00 ± 0.89 | 177.50 ± 1.23 | 165.30 ± 2.12** | 140.70 ±1.54*** | 119.00 ± 1.25*** |
| III | Glibenclamide (1 mg/kg) |
84.00 ± 0.77 | 141.2±1.19*** | 134.00 ±1.63*** | 128.20 ± 1.81*** | 97.33 ± 2.216*** |
| IV | Diabetic control | 171.70 ±12.40 | 472.80 ± 7.43 | 550.00 ± 0.00 | 550.00 ± 0.00 | 550.00 ± 0.00 |
| V | STZ + C. pentandra extract (200 mg/kg) |
153.20 ± 6.84 | 269.30 ± 7.88*** | 340.30 ± 9.38*** | 393.50 ± 4.22*** | 497.00 ± 3.62** |
| VI | STZ + Glibenclamide (1 mg/kg) |
169.20 ± 9.69 | 289.20 ± 7.51*** | 388.50 ± 10.50*** | 460.00 ± 9.76*** | 455.20 ± 10.82*** |
Values are mean ± SEM, (n = 6), ***p<0.001, **p<0.01.
Statistically significant p<0.001, p<0.01 compared to their respective control group