Figure 3.
Weighted principal coordinates analysis (PCoA) of the UniFrac distance measures from the colonic mucosal samples. This analysis was performed to demonstrate relative distances (i.e. maximal differences) between the microbiota of each sample (colonic mucosa of each animal studied) at the genera level in a 2 dimensional space A. The Smad4+/− (grey diamond) and the wild type (WT; black dot) microbiota did not separate distinctly. B. The microbiota of colitis-prone (grey diamond) Smad4+/− mice segregated from the non-colitic (black diamond) Smad4+/− animals.