Entire recording from one subject. The vertical dashed lines indicate the beginning of handgrip, the end of handgrip and beginning of ischaemia, and the end of ischaemia. The horizontal lines indicate average control values. As expected, muscle sympathetic nerve activity and arterial pressure increased during handgrip, and R-R intervals decreased. The major observation in this recording is that after handgrip, vagal baroreflex gain oscillated in major ways (Panel E, right).