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. Author manuscript; available in PMC: 2015 Jan 1.
Published in final edited form as: Arch Biochem Biophys. 2013 Nov 4;541:10.1016/j.abb.2013.10.021. doi: 10.1016/j.abb.2013.10.021

Figure 1.

Figure 1

DRE-like DNA elements (A) and chemicals (B) previously reported to induce AhR:ARNT-dependent reporter gene expression in a ligand-selective manner. Alignment of DRE-like sequences from the promoter regions of the murine Bax and human paraoxonase 1 (PON1) genes are shown along with the wild type DRE3. The DRE core nucleotides are boxed, and underlined bases represent mutations in the wild type Bax DRE-like response element that reportedly restore TCDD-responsiveness [12].