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. Author manuscript; available in PMC: 2014 Oct 4.
Published in final edited form as: J Proteome Res. 2013 Sep 18;12(10):10.1021/pr4005103. doi: 10.1021/pr4005103

Figure 7.

Figure 7

Immunohistochemical analysis of phospho Tau in CVN-AD versus wild-type mice. The phosphorylation of tau was compared between CVN-AD and wild-type mice at 6, 12, 24 and 42 weeks of age using immunohistochemistry on brain sections. AT8 immunoreactivity, corresponding to double phosphorylation at pS202/pT205, is evident in the CA1 and subiculum (S) at 12 weeks in CVN and increases in severity with age. At 42 weeks immunoreactivity is evident in the dentate gyrus (DG). Subiculum scale bars = 100um. Hippocampus scale bars = 500um.