Table 4. Male AGA-associated genotypes and risk allele frequencies.

Marker	Chr.		Type I–III	Type IV–VII	Odds ratio (95% CI)	P valuea	P valueb
rs1998076	20	Genotype (n)	123	55		1.25E-2	0.10
		GG	39	30	1 [Reference]
		AG	70	22	0.41 (0.21–0.80)	1.12E-2
		AA	14	3	0.28 (0.07–1.06)	0.06
		Dominant model
		GG	39	30	1 [Reference]
		AG+AA	84	25	0.39 (0.20–0.74)	5.31E-3
		Recessive model
		GG+AG	119	52	1 [Reference]
		AA	14	3	0.45 (0.12–1.63)	0.22
		Risk allele frequency			0.52 (0.31–0.85)	1.87E-3
		G	0.60	0.75
		A	0.40	0.25
rs913063	20	Genotype	124	56		0.04	0.32
		CC	58	24	1 [Reference]
		CA	57	17	0.72 (0.35–1.48)	0.37
		AA	9	15	4.03 (1.55–10.45)	4.08E-3
		Dominant model
		CC	58	24	1 [Reference]
		CA+AA	66	32	1.17 (0.62–2.21)	0.63
		Recessive model
		CC+CA	115	41	1 [Reference]
		AA	9	15	4.68 (1.90–11.50)	7.44E-4*
		Risk allele frequency			1.67 (1.05–2.65)	0.03
		C	0.70	0.58
		A	0.30	0.42
rs1160312	20	Genotype	126	57		0.03	0.19
		GG	59	24	1 [Reference]
		AG	57	17	0.73 (0.36–1.51)	0.40
		AA	10	16	3.93 (1.57–9.89)	4.58E-3
		Dominant model
		GG	59	24	1 [Reference]
		AG+AA	67	33	1.21 (0.64–2.28)	0.55
		Recessive model
		GG+AG	116	41	1 [Reference]
		AA	10	16	4.53 (1.90–10.77)	8.75E-4*
		Risk allele frequency			1.71 (1.08–2.71)	1.71E-2
		G	0.69	0.57
		A	0.31	0.43
rs201571	20	Genotype	123	55		9.85E-3*	0.06
		CC	61	23	1 [Reference]
		CT	52	16	0.82 (0.39–1.71)	0.59
		TT	10	16	4.24 (1.68–10.69)	2.19E-3
		Dominant model
		CC	61	23	1 [Reference]
		CT+TT	62	32	1.37 (0.72–2.60)	0.34
		Recessive model
		CC+CT	113	39	1 [Reference]
		TT	10	16	4.64 (1.94–11.06)	4.87E-4*
		Risk allele frequency			1.87 (1.17–2.98)	2.49E-3
		C	0.71	0.56
		T	0.29	0.44

Statistical significance with Bonferroni Correction (P<1.14E-2).

^a The correlation analysis between AGA and genotype and between AGA and risk allele frequency was performed using logistic regression and chi-square test.

^b Verification of Hardy-Weinberg equilibrium.