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. 2013 Dec 30;8(12):e82949. doi: 10.1371/journal.pone.0082949

Figure 6. The role of the SDF-1-CXCR4 pathway in the homing of MSCs.

Figure 6

(A) Kidney uptake of eGFP-labeled MSCs was measured by fluorescence microscopy 48 h after systemic administration (a: MSCsCXCR4 /GFP, b: MSCsGFP, c: MSCsshCXCR4/GFP). Labeled cells were detected surrounding the glomerulus (arrows). (B and C) Chemotaxis into transplanted kidneys was measured by RT-PCR andWestern blot. Recipients treated with MSCsGFP were used as control. ★P<0.05 vs. control. (D) The expression of eGFP in different organs from recipient rats was measured 48 h after infusion.