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. 2013 Dec 30;8(12):e83168. doi: 10.1371/journal.pone.0083168

Figure 3. Blood glucose (BG) threshold for seizures in CON vs. STZ rats and association with survival and seizures after treatment.

Figure 3

A. Initial BG (prior to insulin IP) is significantly lower in CON (6.3±0.3 mM; n = 16) than in STZ rats (12.4±1.3 mM; n = 22) (p<0.01). BG at seizure onset (observed seizure score ≥2.5) is similar in CON (1.6±0.1 mM) and STZ rats (1.8±0.2 mM) B: No significant association between BG levels at seizure onset and post-treatment seizures. BG levels glucose at seizure onset for CON: 1 seizure; 1.7 ±0.2 mM (n = 11) and >1 seizure; 1.6±0.1 mM (n = 5) and STZ: 1 seizure; 1.9±0.2 mM (n = 10), >1 seizure; 1.9±0.3 mM (n = 12) are not statistically different C: No significant difference between BG levels at seizure onset comparing survival and mortality. BG for CON: S+S; 1.7±0.1 mM (n = 11) and S+M; 1.5 ±0.1 mM (n = 5); STZ: S+S; 1.8±0.2 mM (n = 17) and S+M; 2.2±0.32 mM (n = 5) are not significantly different.