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. 2013 Dec 30;8(12):e84065. doi: 10.1371/journal.pone.0084065

Table 1. MIC (µg/mL) of the 15 antimicrobial agents* to the 24 standard NTM strains.

Species(Code) RIF INH STR AK KM CP OF LOF CAP CEF DOX MIN ETH PAS DIP
M. abscessus (ATCC19977) RGM >256 >256 32 32 128 4 32 16 >256 64 >256 >42.5 16 >256 >256
M. chelonae (NCTC946) RGM 64 >256 16 32 64 1 4 2 >256 >256 >256 >42.5 16 >256 >256
M. fortuitum (ATCC6841) RGM 64 >256 128 4 8 <0.25 <0.25 <0.5 >256 32 >256 >42.5 64 >256 >256
M. peregrinum (ATCC14467) RGM 2 >256 32 <0.5 4 <0.25 <0.25 <0.5 >256 8 64 10.7 4 >256 >256
M. doricum (ATCCBAA565) RGM 64 >256 64 4 16 <0.25 0.5 <0.5 >256 >256 >256 >42.5 32 >256 >256
M. obuense (ATCC27023) RGM 16 >256 <0.5 1 4 <0.25 0.5 <0.5 >256 >256 2 1.3 8 >256 >256
M. phlei (ATCC11758) RGM <0.5 >256 <0.5 <0.5 8 0.5 1 <0.5 >256 16 <0.5 3 4 >256 >256
M. duvalii (ATCC43910) RGM <0.5 >256 <0.5 <0.5 1 <0.25 <0.25 <0.5 >256 8 <0.5 0.3 2 >256 >256
M. parafortuitum (ATCC19686) RGM 4 >256 <0.5 1 4 <0.25 <0.25 <0.5 >256 >256 <0.5 0.3 8 >256 >256
M. gilvum (ATCC43909) RGM <0.5 >256 4 1 2 <0.25 <0.25 <0.5 >256 >256 1 1.3 2 >256 >256
M. flavescens (ATCC14474) RGM 16 >256 2 <0.5 1 <0.25 0.5 <0.5 >256 >256 1 0.7 8 >256 >256
M. bolletii (CIP 108541) RGM >256 >256 128 16 64 8 64 32 >256 64 >256 >42.5 16 >256 >256
M. intracellulare (ATCC13950) SGM 2 >256 4 4 16 1 16 4 >256 >256 4 1 8 >256 >256
M. xenopi (NCTC10042) SGM 1 >256 1 1 - <0.25 <0.25 <0.5 256 64 <0.5 <0.08 8 >256 >256
M. senegalense (ATCC35796) SGM 2 >256 16 2 2 2 4 1 >256 16 1 0.17 8 >256 >256
M. gordonae (ATCC14470) SGM <0.5 >256 1 2 4 1 2 0.5 32 >256 4 5 4 >256 >256
M. marinum (ATCC927) SGM <0.5 >256 4 1 8 4 16 32 >256 32 <0.5 0.7 4 >256 128
M. kansasii (ATCC12478) SGM <0.5 >256 1 4 4 <0.25 0.5 <0.5 >256 8 2 2.7 4 >256 >256
M. scrofulaceum (ATCC19981) SGM 0.5 >256 1 2 4 <0.25 1 <0.5 4 >256 2 1 2 >256 >256
M. malmoense (ATCC29571) SGM 1 >256 2 2 4 0.5 1 <0.5 >256 >256 8 5 4 >256 >256
M. avium (ATCC25291) SGM 8 >256 1 2 16 2 4 2 >256 >256 32 11 4 >256 >256
M. szulgai (NCTC10831) SGM <0.5 >256 2 4 8 1 2 2 >256 16 4 2.7 8 >256 >256
M. terrae (ATCC15755) SGM 1 >256 4 8 16 <0.25 <0.25 <0.5 >256 4 8 1 16 >256 >256
M. simiae (ATCC25275) SGM 8 >256 16 8 64 32 64 16 >256 >256 >256 >42.5 16 >256 >256

MIC, minimum inhibitory concentration; NTM, nontuberulous mycobacteria; RGM, rapidly growing mycobacteria; SGM, slowly growing mycobacteria; RIF, rifampicin; INH, isoniazid; STR, streptomycin; AK, amikacin; KM, kanamycin; CP, ciprofloxacin; OF, ofloxacin; LOF, levofloxacin; CAP, capreomycin; CEF, cefoxitin; DOX, doxycycline; MIN, minocycline; ETH, ethionamide; PAS, P-aminosalicylic acid; DIP, dipasic.

bold typeface indicates that the species was susceptible to the antimicrobial drug, while underlining indicates that the species was moderately susceptible to the antimicrobial drug.