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. 2013 Dec 23;9:183–195. doi: 10.2147/IJN.S49460

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© 2014 Kamath et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License

The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.

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Alkaline phosphatase assay showing fold increase against PCL (positive control) activity taken as 100%. (A) Alkaline phosphatase assayed on day 8 shows significantly increased activity in PCL-RNP (P ≤ 0.001) and PCL-Res (P ≤ 0.001) compared with PCL (positive control) and (B) on day 12 of culture on scaffolds shows significantly increased activity in PCL-RNP (P ≤ 0.001) and PCL-Res (P ≤ 0.001) compared with PCL (positive control).

Note: Positive control, cell culture done on PCL scaffold in osteogenic medium; negative control, cell culture done on PCL scaffold in DMEM-LG medium.

Abbreviations: PCL, polycaprolactone; RNP, resveratrol-loaded albumin nanoparticles; Res, resveratrol; DMEM-LG, Dulbecco’s Minimum Essential Medium-Low Glucose.