Skip to main content
. 2013 Dec 30;8(12):e84089. doi: 10.1371/journal.pone.0084089

Figure 4. sarA dictates the extent of proinflammatory mediator expression during CNS catheter-associated infection.

Figure 4

Catheter-associated infections were generated with either wild type ACH1719 (WT) or ACH1719ΔsarA (Δ sarA). The tissue surrounding the infected catheters was homogenized and the resulting supernatant analyzed for levels of the pro-inflammatory mediators CXCL1 (A, B) and IL-1β (C, D). Results are presented as raw data (A and C) and after adjustment for divergent bacterial burdens (B and D). * = p<0.05 (n = 11–21 mice/group/time point).