Table 1. Characteristics of children in the training and validation groups.
Training group
|
Validation group
|
p value | ||||
---|---|---|---|---|---|---|
n= 485 | % | n= 976 | % | |||
Neonatal characteristics | ||||||
Gestational age (weeks) | ||||||
24-27 weeks | 102 | (21 | 220 | 22 | 0.57 | |
28-29 weeks | 107 | (22 | 229 | 24 | ||
30-32 weeks | 276 | (57 | 527 | 54 | ||
Birth weight Z-score | ||||||
<-1 SD | 96 | (20) | 217 | (22) | 0.41 | |
(-1 ; 0) SD | 204 | (42) | 477 | (43) | ||
> 0 SD | 185 | (38) | 342 | (35) | ||
Female | 215 | (44) | 439 | (45) | 0.83 | |
Mean creatinine ( mg/dl) | ||||||
24-27 weeks | 1.4 | (0.7) | 1.4 | (0.7) | 0.27 | |
28-29 weeks | 0.8 | (0.4) | 0.8 | (0.3) | ||
30-32 weeks | 0.7 | (0.4) | 0.7 | (0.3) | ||
Number of creatinine assessment | ||||||
24-27 weeks | 20 | (17) | 22 | (18) | 0.78 | |
28-29 weeks | 11 | (10) | 11 | (9) | ||
30-32 weeks | 5 | (6) | 6 | (7) | ||
Sodium variation (meq/l) | ||||||
24-27 weeks | 21 | (11) | 20 | (10) | 0.98 | |
28-29 weeks | 14 | (10) | 14 | (7) | ||
30-32 weeks | 9 | (6) | 9 | (6) | ||
Patent ductus arteriosus | 59 | (12) | 119 | (12) | 0.98 | |
Catecholamine treatment | 42 | (9) | 70 | (7) | 0.32 | |
Nosocomial infection | 123 | (25) | 280 | (29) | 0.18 | |
Bronchodysplasia: oxygenotherapy | ||||||
No oxygen | 269 | (56) | 491 | (50) | 0.09 | |
< 28 days | 131 | (27) | 323 | (33) | ||
28 days- 36 weeks of GA | 58 | (12) | 118 | (12) | ||
> 36 weeks of GA | 27 | (6) | 44 | (5) | ||
Cerebral lesions | 17 | (4) | 64 | (7) | 0.02 | |
Neonatal surgery | 46 | (10) | 86 | (9) | 0.67 | |
Necrotizing enterocolitis | 11 | (2) | 30 | (3) | 0.38 | |
Neonatal outcome | ||||||
Death | 35 | (7) | 82 | (8) | 0.43 | |
Alive | 450 | (93) | 894 | (92) | ||
Outcome at 2 years | n= 396 | (%) | n= 784 | (%) | ||
Optimal outcome | 269 | (68) | 550 | (70) | 0.31 | |
Non-optimal outcome | 85 | (22) | 179 | (23) | ||
Missing data | 35 | (9) | 51 | (7) | ||
Genetic anomalies | 6 | (2) | 2 | (3) | ||
death | 1 | (3) | 2 | (3) |