Table 3. Identification of Raman peaks vs. vibrational modes for Tenofovir.
| Raman Shift ( cm-1 ) | Tentative Assignment | References |
|---|---|---|
| 537 (w) a | δ(C-C=C) b | [74] |
| 614 (vw) | δ(N-C-C) | [74] |
| 725 (vs) | Adenine ring breathing (in-phase stretching) | [74,75] |
| 802 (vw) | ν(C-C) | [74] |
| 841 (w) | β(skel) | [74] |
| 876 (vw) | γ,δ(N-H) | [74] |
| 905 (vw) | r(NH2) | [74] |
| 942 (vw) | δ(N-C=N) | [74] |
| 973 (w) | Phosphate | [76] |
| 1007 (w) | Phosphate | [76] |
| 1255 (mw) | ν(C-NH2); ν(C=N); ν(C-N); δ(C-H) | [74,75] |
| 1311 (ms) | ν(C-N); ν(C=N); δ(C-H) | [74-76] |
| 1335 (s) | ν(C-N); ν(C=N); w(CH2) | [74,77] |
| 1370 (ms) | δ(C-H); γ,δ(C-H) | [74] |
| 1423 (w) | δ(N=CH); w(CH3) | [74,77] |
| 1486 (w) | δ(NH2) | [74] |
| 1517 (m) | δ(C-N-H); Imidazole ring | [74,75] |
| 1581 (mw) | ε(NH2) | [77] |
a vs, very strong; s, strong; ms, medium-strong; m, medium; mw, medium-weak; w, weak; vw, very weak.
b δ, bending; ν, stretching; r, rocking; w, wagging; ε, scissoring; β, in-plane; γ, out-of-plane; skel, skeleton vibration