Table 5. Limit of detection (LOD) with the Horiba Raman system for Tenofovir, IQP-0528 and Dapivirine in different media.

Drugs	Media	LOD (%w/w)
Tenofovir	Water	0.01
	Gel	0.02
	Porcine tissue homogenate	0.04
IQP-0528	Ethanol	0.01
	Gel	0.03
	Porcine tissue homogenate	0.04
Dapivirine	70/30 iprOH/water	0.003
	Gel	0.006
	Porcine tissue homogenate	0.006