Table 3. The prevalence of MYO9B haplotypes in the combined Dutch and German cohorts of patients with acute pancreatitis and controls reconstructed from genotyped SNPs and their association with acute pancreatitis.
|
MYO9B haplotypes |
|||||||||
|---|---|---|---|---|---|---|---|---|---|
| rs7259292 | rs2305767 | rs1545620 | rs1457092 | rs2305764 | Cases (%) | Controls (%) | OR | 95% CI | P-value* |
| C | G | A | C | G | 460 (38) | 900 (42) | 1.00‡ | – | ref |
| C | A | C | A | A | 443 (37) | 700 (33) | 1.24 | 1.05-1.46 | 0.0099 |
| C | A | A | C | G | 190 (16) | 365 (17) | 1.02 | 0.83-1.25 | 0.8860 |
| C | A | A | C | A | 40 (3.3) | 98 (4.6) | 0.81 | 0.55-1.19 | 0.2512 |
| T | A | C | C | G | 52 (4.3) | 50 (2.3) | 2.03 | 1.36-3.04 | 0.0005 |
OR, odds ratio; 95% CI, 95% confidence interval.
* Two-tailed P-values were calculated by chi-squared test for independence of haplotype counts.
‡ This haplotype was taken as the reference.
Risk alleles are in bold and underlined.