Figure 5. IL-13 induces airway epithelial barrier dysfunction similar to IL-4. (A) 16HBE cells were incubated with IL-4 or IL-13 (50 ng/ml each) alone or in combination followed by analysis of TEER over time (A) or paracellular permeability to 3-kDa dextran after 72 h (B). Results in (A) are normalized to control TEER, which was set as 100. Data are the mean ± SEM of n = 3 experiments. * indicates p < 0.05 compared with the control cells.