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. Author manuscript; available in PMC: 2015 Jun 1.
Published in final edited form as: Biomech Model Mechanobiol. 2013 Jul 30;13(3):551–563. doi: 10.1007/s10237-013-0517-9

Fig. 6.

Fig. 6

TSNIT plot of the estimated mean maximum principal strain at 45 mmHg (assuming zero deformation at 5 mmHg and a 40 mmHg IOP elevation) in the peripapillary region, as predicted by the statistical model for 20 and 90 years old. The 95% credible intervals of the estimated means of strain values are indicated by the color-shaded areas around each curve. On average, the nasal sectors exhibit the highest strains when humans are young, but that reverses with age such that the temporal sectors exhibit the highest strains in the elderly. Sectorial strain variability decreases with age due to the gradual overall stiffening of the sclera with age. T, temporal; S, superior; N, nasal; I, inferior