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. 2013 Apr 10;1(3):e24517. doi: 10.4161/tisb.24517

Table 1. Summary of Claudin expression patterns.

  1* 2 3 4 5* 8 10 11 12 14 15 16 17 18 22 23
Gastrulation (HH4 - HH7)
Epiblast ++ + + + - + + + + + + + + + + +
Mesoderm - + - + - - + - - - + - + - - +
Endoderm + + - + - + + + - + + + + + - +
Hensen's node - + - + - + +a - - + + + + + - +
Extraembryonic ectoderm + + + + + + + + + + + + + + + +
Neurulation (HH8-HH12)                                
Neural ectoderm - + - + - + + - - + + + + + - +
Non-neural ectoderm + + ++ + - + ++ ++ + + + + + + ++ +
Pharynx + + ++ ++ - + - - - ++ + + ++ + + +
Heart - ++ - - - - + - - + - - - - - -
Somites - + - - - - - - - - - - - - - -
Vasculature - - - - ++ - - - - - - - - - - -
Organogenesis (E3-E10)                                
Eye epithelium + +b + + - + +b - - + + + + + + -
Otic vesicle +b - ++b + - + + + +b + +b + - - - -
Nasal epithelium + + + - - +b +b +b +b +b +b +b +b +b - +b
Limb ectoderm + + + + - + + + + + + + + + + +
Apical ectodermal ridge + - + + - - - + + - - + - + + -
Surface ectoderm + + ++b + - + +b +b +b + +b + + + +b +
Feather buds + - + + - - - - - - - - - - - -
Pancreas + - + + - - - + - - - - - - - -
Lung + - + - - - + - - - - - - - - -
Kidney + - + + - - ++ - - - - - - - - -
Gonad n/a - - - - - - ++ - - - - - - - -
Heart - + - - - - - + - - - + + - - +
*

, the expression patterns of Claudin-1 and Claudin-5 have been published previously; -, absent expression; +, positive expression; ++, robust expression ; +a, asymmetric expression; +b, expression with boundaries