Table 1. Metabolic changes.
| Statistical comparisons: Welch 2-sample t test | |||||
|---|---|---|---|---|---|
|
Significantly altered biochemicals |
Methotrexate |
|
|
|
|
|
10 nM Control |
100 nM Control |
Infliximab IgG1K |
IgG1K Control |
Infliximab Control |
|
| Total biochemical: P ≤ 0.05 |
0 |
5 |
0 |
0 |
3 |
| Biochemicals (↑↓) |
0|0 |
4|1 |
0|0 |
0|0 |
1|2 |
| Total biochemical: 0.05 < P < 0.10 |
6 |
1 |
3 |
2 |
2 |
| Biochemicals (↑↓) | 5|1 | 1|0 | 1|2 | 2|0 | 2|0 |
Welch 2-sample t-test was used to determine whether the means of the two populations are different. A total of 148 metabolites were identified. Red indicates an increase; green indicates a reduction. Original data are shown in Table S1.