Figure 1. Expression of mTORC1/2 pathway components in CoCSC-derived cultures and xenografts.

Immunofluorescence pictures of Tu22 showing (A) expression of distinct mTOR pathway components, and (B) co-localization of mTOR Ser2481 and γ-tubulin. Scale bars, 100μm. (C) Hematoxylin and eosin (H&E), immunohistochemistry (AEC, red color) or immunofluorescence staining for different mTOR pathway components on PFA-fixed, paraffin-embedded serial sections of Tu12-derived xenografts. Scale bar, 100μm.