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. 2004 Apr;42(4):1713–1715. doi: 10.1128/JCM.42.4.1713-1715.2004

TABLE 3.

Comparison of LD50 of botulinum toxins produced at 30 and 37°C by C. botulinum strain 93-197

Dilution No. of mice alive/no. tested after incubation of culture at:
30°C 37°C
1:1,280 0/2 0/2
1:2,560 0/2 0/2
1:5,120 1/2a 0/2
1:10,240 2/2 0/2
1:20,480 2/2 1/2b
1:40,960 2/2 2/2
a

The LD50 of type F toxin was 1:5,120 at 30°C; at this dilution and temperature, the LD50 of type B toxin was <1.

b

The LD50 of type B toxin was 1:20,480 at 37°C; at this dilution and temperature, the LD50 of type F toxin was <1.