Table 2.
Eligibility criteria for review on Ki67 index.
| Study characteristics | Inclusion criteria | Exclusion criteria |
| Participants/population | Patients with primary neuroendocrine tumors who were assessed with Ki67 index, mitotic count or tumor grading | Patients over the age of 18 years old |
| Tumor markers | Tumor markers (Ki67 index, mitotic count or tumor grading) must be obtained from the primary tumor | Studies that do not report the predictive value of Ki67 index, mitotic count or tumor grading |
| Study design | Follow-up studies for the development of liver metastases | No follow-up studies for the development of liver metastases |
| Randomized controlled trials (RCTs) | ||
| Prospective and retrospective comparative cohort studies | Case reports | |
| Noncomparative cohort studies | ||
| Case-control studies | Reviews | |
| Case series |