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. 2004 Apr;42(4):1631–1636. doi: 10.1128/JCM.42.4.1631-1636.2004

TABLE 2.

Run-to-run precision: stratified by ranges of HCV core antigen assay concentrationa

Range of HCV core Ag concn (pg/ml) % of specimens in rangea Specimen HCV core Ag (pg/ml)
CV (%) Mean CV (%)
1st run 2nd run Mean SD
1.5-25 18 2536 2.1 1.7 1.9 0.28 15 9.7
2530 8.3 7 7.7 0.92 12
2515 9.1 7.9 8.5 0.85 10
2387 19.4 18.7 19.1 0.49 3
2438 22.1 19.4 20.8 1.91 9
26-50 8.3 2456 35.8 30.6 33.2 3.68 11 6.8
2543 38.7 43 40.9 3.04 7
2481 41.6 45.4 43.5 2.69 6
2318 42 37.5 39.8 3.18 8
2555 46 46.9 46.5 0.64 1
51-75 4.3 1166 52.8 53.2 53 0.28 1 1.67
0248 56.1 55.6 55.9 0.35 1
2521 61.3 59 60.2 1.63 3
2557 74.1 70.4 72.3 2.62 4
2414 74.5 75.4 75 0.64 1
76-100 5.1 2392 76.4 81.6 79 3.68 5 6.88
2258 80.1 78 79.1 1.48 2
2042 84.3 92.5 88.4 5.8 7
2274 86.8 78.9 82.9 5.59 7
2336 96.3 78.3 87.3 12.7 15
101-125 4.5 2436 102.2 92.9 97.6 6.58 7 7.77
2498 102.4 91.7 97.1 7.57 8
2422 107.6 99.4 103.5 5.8 6
2243 114 97.2 105.6 11.9 11
2235 117 105.3 111.2 8.3 7
126-150 4.0 2256 127.7 103.3 115.5 17.3 15 8.57
1787 129.7 129.1 129.4 0.42 0
829 136.3 158.3 147.3 15.6 11
1037 138.5 157.4 148 13.4 9
2499 146.9 131.2 139.1 11.1 8
a

Among 629 HCV core Ag-positive specimens in Table 1, 44.0% are represented in the ranges in this table (i.e., 1.5 to 150 pg/ml).