TABLE 2.
Run-to-run precision: stratified by ranges of HCV core antigen assay concentrationa
Range of HCV core Ag concn (pg/ml) | % of specimens in rangea | Specimen | HCV core Ag (pg/ml)
|
CV (%) | Mean CV (%) | |||
---|---|---|---|---|---|---|---|---|
1st run | 2nd run | Mean | SD | |||||
1.5-25 | 18 | 2536 | 2.1 | 1.7 | 1.9 | 0.28 | 15 | 9.7 |
2530 | 8.3 | 7 | 7.7 | 0.92 | 12 | |||
2515 | 9.1 | 7.9 | 8.5 | 0.85 | 10 | |||
2387 | 19.4 | 18.7 | 19.1 | 0.49 | 3 | |||
2438 | 22.1 | 19.4 | 20.8 | 1.91 | 9 | |||
26-50 | 8.3 | 2456 | 35.8 | 30.6 | 33.2 | 3.68 | 11 | 6.8 |
2543 | 38.7 | 43 | 40.9 | 3.04 | 7 | |||
2481 | 41.6 | 45.4 | 43.5 | 2.69 | 6 | |||
2318 | 42 | 37.5 | 39.8 | 3.18 | 8 | |||
2555 | 46 | 46.9 | 46.5 | 0.64 | 1 | |||
51-75 | 4.3 | 1166 | 52.8 | 53.2 | 53 | 0.28 | 1 | 1.67 |
0248 | 56.1 | 55.6 | 55.9 | 0.35 | 1 | |||
2521 | 61.3 | 59 | 60.2 | 1.63 | 3 | |||
2557 | 74.1 | 70.4 | 72.3 | 2.62 | 4 | |||
2414 | 74.5 | 75.4 | 75 | 0.64 | 1 | |||
76-100 | 5.1 | 2392 | 76.4 | 81.6 | 79 | 3.68 | 5 | 6.88 |
2258 | 80.1 | 78 | 79.1 | 1.48 | 2 | |||
2042 | 84.3 | 92.5 | 88.4 | 5.8 | 7 | |||
2274 | 86.8 | 78.9 | 82.9 | 5.59 | 7 | |||
2336 | 96.3 | 78.3 | 87.3 | 12.7 | 15 | |||
101-125 | 4.5 | 2436 | 102.2 | 92.9 | 97.6 | 6.58 | 7 | 7.77 |
2498 | 102.4 | 91.7 | 97.1 | 7.57 | 8 | |||
2422 | 107.6 | 99.4 | 103.5 | 5.8 | 6 | |||
2243 | 114 | 97.2 | 105.6 | 11.9 | 11 | |||
2235 | 117 | 105.3 | 111.2 | 8.3 | 7 | |||
126-150 | 4.0 | 2256 | 127.7 | 103.3 | 115.5 | 17.3 | 15 | 8.57 |
1787 | 129.7 | 129.1 | 129.4 | 0.42 | 0 | |||
829 | 136.3 | 158.3 | 147.3 | 15.6 | 11 | |||
1037 | 138.5 | 157.4 | 148 | 13.4 | 9 | |||
2499 | 146.9 | 131.2 | 139.1 | 11.1 | 8 |
Among 629 HCV core Ag-positive specimens in Table 1, 44.0% are represented in the ranges in this table (i.e., 1.5 to 150 pg/ml).